Figure 3
From: Essentiality and centrality in protein interaction networks revisited
Essential and MDSet proteins in protein complexes. We calculated the complex participation coefficients of all proteins in the binary interaction networks of E. coli, S. cerevisiae and H. sapiens. Specifically, e-MDSet proteins reached into more complexes compared to essential proteins in E. coli (P = 1.9 × 10−4, Wilcoxon test), S. cerevisiae (P = 3.5 × 10−6,) and H. sapiens (P = 9.6 × 10−11).