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Figure 6 | BMC Bioinformatics

Figure 6

From: A strategy to build and validate a prognostic biomarker model based on RT-qPCR gene expression and clinical covariates

Figure 6

The validation surprise observed with strategy B (PCR batch level sampling) is smaller than the validation surprise observed with strategy A (patient level sampling). Strategy A cross-validated time-dependent AUC (blue); strategy B cross-validated time-dependent AUC (red); validated time-dependent AUC on the test dataset (black) and bootstrap confidence intervals (grey polygon) (95% of the boostrap samples distribution) for the Lasso_Cox −4 model.

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