Comparison of pores extracted by MOLE and CHEXVIS in 3EAM.(a) Cartoon representation of the transmembrane protein 3EAM. The 3D view is such that the transmembrane pore is perpendicular to the plane of the page. (b) The pores extracted by MOLE in this structure. MOLE identifies a few side channels going from central pore to outside, but it fails to identify the transmembrane pore. (c) On the other hand, CHEXVIS identifies the main transmembrane pore as well as some side channels. (d) Also, the top transmembrane pore suggested by CHEXVIS is verified to be the correct transmembrane pore in this structure .