Figure 3

Classification accuracy of SomInaClust on the pooled set of putative driver genes in 9 solid cancers. TSG scores are plotted as a function of OG scores for all genes that were 1) retrieved by SomInaClust in the 9 solid cancers analysed and 2) present in the CGC list. Genes that are known to be dominant are shown in red, while recessive genes are shown in green. The legend indicates the cancer type and is shown on the top right. Dashed lines indicate cut-offs for classification as oncogene or as tumour suppressor genes. Genes in the lower right part are classified as oncogenes, in the upper (left and right) part as tumour suppressor genes, while genes in the lower left part are unclassified.