Question | Required | Example | Golden exact | Golden Ideal |
---|---|---|---|---|
type | answer | question | answer | answer |
Yes/No | Exact + Ideal | Is miR-21 related to carcinogenesis? | Yes | Yes. It has been demonstrated in several experimental studies that miR-21 has oncogenic potential, and is significantly disregulated in numerous types of cancer. Therefore, miR-21 is closely related to carcinogenesis. |
Factoid | Exact + Ideal | Which is the most common disease attributed to malfunction or absence of primary cilia? | āautosomal recessive polycystic kidney diseaseā | When ciliary function is perturbed, photoreceptors may die, kidney tubules develop cysts, limb digits multiply and brains form improperly. Malformation of primary cilia in the collecting ducts of kidney tubules is accompanied by development of autosomal recessive polycystic kidney disease. |
List | Exact + Ideal | Which human genes are more commonly related to craniosynostosis? | [āMSX2ā, āRECQL4ā, āSOX6ā, āFGFR1ā, āFGFR2ā, āFGFRā] | The genes that are most commonly linked to craniosynostoses are the members of the Fibroblast Growth Factor Receptor family FGFR3 and to a lesser extent FGFR1 and FGFR2. Some variants of the disease have been associated with the triplication of the MSX2 gene and mutations in NELL-1. |
Summary | Ideal | What is the mechanism of action of abiraterone? | - | Abiraterone acts by inhibiting cytochrome P450 170Ģ3b1-hydroxylase (CYP17A1), a critical step in androgen biosynthesis, thus leading to inhibition of androgen biosynthesis. |