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Figure 2 | BMC Bioinformatics

Figure 2

From: Probing long-range interactions by extracting free energies from genome-wide chromosome conformation capture data

Figure 2

Free energy principal components and chromatin-binding profiles. Shown are the first four principal components (A, B, C, D) calculated genome-wide from the F i,j matrix created from the raw + ICE contact matrix (top plots). Below each free energy profile are heat maps of the genome-wide average binding profiles for the selected chromatin factors (see Text). The top heat map corresponds to the positive free energy interaction profile (blue curve), and the bottom heat map for that of the inverse profile (red curve). Red regions in the heat maps represent locations of higher occupancy and blue regions represent lower occupancy. The range of the heat maps goes from 0.0 (blue) to 1.0 (red).

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BMC Bioinformatics

ISSN: 1471-2105

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