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Table 9 The top 1% (e.g., 15) CC-MDS proteins in the combined network

From: Determining minimum set of driver nodes in protein-protein interaction networks

Protein

# GO terms

E

A

GD

OD

UD

VT

TF

PK

AKT1

326

x

x

x

x

x

  

x

EGFR

315

x

x

x

x

x

  

x

MAPK3

308

 

x

     

x

TGFB1

302

x

x

x

x

x

   

CDK1

293

x

x

   

x

  

SIRT1

292

x

x

      

CTNNB1

289

x

x

x

x

x

   

MAPK1

284

x

    

x

 

x

RPS27A

279

     

x

  

INS

272

x

x

x

x

x

   

UBC

272

x

       

IGF1

269

x

x

x

x

x

   

LYN

269

    

x

x

 

x

TRAF6

267

x

    

x

  

SRC

264

x

  

x

x

x

 

x

  1. If a protein is an essential (“E”) gene, aging (“A”) gene, GAD disease (“GD”) gene, OMIM disease (“OD”) gene, Uniport disease (“UD”) gene, virus-targeted (“VT”) gene, transcription factors (“TF”) or protein kinase (“PK”), there is an “x” in the corresponding entry.
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BMC Bioinformatics

ISSN: 1471-2105

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