Mirinho: An efficient and general plant and animal pre-miRNA predictor for genomic and deep sequencing data

BMC Bioinformatics

Table 3 Comparison of the sensitivity, precision and specificity using as input the pre-miRNA dataset D3

	CSHMM	MIRPARA	MIRINHO	MIRENA
	24760.118s	4376.739s	1.251s	3345.317s
Sensitivity	100	88	97	95
Precision	49	84	72	94
Specificity	0	84	64	94
Sensitivity	100	93	98	97
Precision	38	78	71	91

The first three lines contain the results when using the original dataset with 163 positive pre-miRNAs and 168 pseudo pre-miRNAs. The last two lines contain the results when using only the 102 positive pre-miRNAs, from the same dataset, annotated with high confidence according to MIRBASE. The energy threshold used in MIRINHO was -20.6 kcal/mol. Values for the three measures are given in percentage.

ISSN: 1471-2105