Fig. 6

Regions of asymmetric substitutions. Each mark represents a position, or contiguous region, where the pattern of substitutions was significantly asymmetric (p-value ≈ 0). Tissues are indicated as BM (bone marrow), LN (lymph node), and SP (spleen); infections status is indicated as SF (single infection) and DF (dual infection). Reference sequence coordinates are showed on the x-axis