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Table 1 Individual random effect meta-regression

From: Factors affecting the accuracy of a class prediction model in gene expression data

Study Factor

Coef*

AIC

P value

Individual explained-variation

Cell type

0.24 +

137.9

0.44

4.87%

Medical question

−0.32 ++

137.8

0.38

2.55%

Sample size

−0.01

135.9

0.10

12.06%

The number of differentially expressed genes

0.21

116.0

<0.001

72.16%

Fold change

1.42

118.1

<0.001

57.31%

Within class correlation

1.74

137.5

0.31

5.80%

  1. * Coefficient of the corresponding study factor in the random effects logistic regression
  2. + Coefficient for the non-blood category in the Cell Type study factor
  3. ++ Coefficient for the non-diagnostic category in the Medical Question study factor