Fig. 5
From: diffHic: a Bioconductor package to detect differential genomic interactions in Hi-C data
Trended dispersions with respect to the average abundance for real data. The trended NB dispersion was computed using edgeR for each 1 Mbp bin pair in each study, after filtering and non-linear normalization. This was done for the Rickman et al. [5], Dixon et al. [4] and Sofueva et al. [16] data sets. The biological coefficient of variation is defined as the square-root of the NB dispersion, and is shown here for improved resolution of low dispersions