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Fig. 4 | BMC Bioinformatics

Fig. 4

From: CompGO: an R package for comparing and visualizing Gene Ontology enrichment differences between DNA binding experiments

Fig. 4

Comparison of CompGO to the overlap method. Differentially enriched GO terms using the overlap method (p ≤ 0.05) for a NKX2-51 vs. NKX2-52 and b NKX2-51 vs. ELK4. c Log odds ratio of NKX2-51 vs. NKX2-52 versus differential p-values returned from DAVID, scored as the difference between –log10 transformed vales. d Log odds ratio of NKX2-51 vs. ELK4 versus differential p-values returned from DAVID, scored as the difference between –log10 transformed vales. Red dots indicate GO terms determined significant and specific using the overlap method. Blue dots are GO terms returned as significant from CompGO. Blue dots with red centres are GO terms returned as significant by both methods. Black dots are non-significant terms using both approaches. For (b) and (c) the density distribution of log odds ratios returned by CompGO is on the top of each panel

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BMC Bioinformatics

ISSN: 1471-2105

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