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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Quantitative gene set analysis generalized for repeated measures, confounder adjustment, and continuous covariates

Fig. 2

Power estimates in the presence of a random effect. Plot of estimated power vs. true fold change differences (effect size) using a significance threshold of 0.05 under a longitudinal gene set simulation (V I F=20.024) with five time points using a random effect for subject. The underestimation of the VIF under QuSAGE yields overly optimistic p-values. Q-Gen remains conservative for an adequate number of replicates

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BMC Bioinformatics

ISSN: 1471-2105

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