Table 5 Examples of correctly predicted missing BP functions by dRW from an older GOA file (date: 2010-01-20) to a recent GOA file (date: 2014-06-09) of Yeast and Human. hCount gives the number of proteins annotated with the term in the older GOA file. Depth represents the term’s depth in the GO hierarchy
From: Predicting protein function via downward random walks on a gene ontology
Yeast | Human | ||||||
|---|---|---|---|---|---|---|---|
Protein | GO terms | hCount | Depth | Protein | GO terms | hCount | Depth |
HIS5 | GO:0001193 | 0 | 8 | EZR | GO:0002143 | 0 | 9 |
PET494 | GO:0019379 | 0 | 5 | TMEM200C | GO:0007094 | 8 | 8 |
CYC1 | GO:0019430 | 0 | 4 | C9orf96 | GO:0016056 | 3 | 7 |
FES1 | GO:0044718 | 0 | 5 | DRGX | GO:0035511 | 0 | 5 |
MET17 | GO:0090334 | 0 | 6 | HDAC7 | GO:0035511 | 0 | 5 |
TSTA3 | GO:2000679 | 2 | 7 | QPRT | GO:0045040 | 0 | 5 |
CSHL1 | GO:0045040 | 0 | 5 | ||||
RGS3 | GO:0060397 | 2 | 7 | ||||
PRDM7_V2 | GO:0071300 | 0 | 6 | ||||
TMEM82 | GO:0090050 | 2 | 7 | ||||