Fig. 2From: A methodology for exploring biomarker – phenotype associations: application to flow cytometry data and systemic sclerosis clinical manifestationsGSEA Schematic. Hybrid Gene Set Enrichment Analysis modeling approach. Conditional Random Forests is first run to generate a Variable Importance List. That list, along with a ranked list of FC variables (ranked by correlation with the phenotype) constitute the input to GSEA. FC sets are created top-down from the Variables Importance ListBack to article page