Fig. 1From: Statistical significance approximation in local trend analysis of high-throughput time-series data using the theory of Markov chainsGeneration of the trend series. The original series X is changed into the trend series d X using the discretizing rules given in equations 1 and 2. Note that the value of \({d^{X}_{i}}\) depends solely on the values of X i+1 and X i but not any other values of XBack to article page