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Table 1 The rank matching scores (RMS) (see Fig. 1) of the signature pathways generated by the DIRAC-based classifier

From: Subtype prediction in pediatric acute myeloid leukemia: classification using differential network rank conservation revisited

Pathways

MLL

t(8;21)

inv(16)

t(15;17)

NUP98.NSD1

CEPBA.dm

NPM1

AGR

    

 

ALK

      

AT1R

      

ATRBRCA

    

  

BCR

 

     

BIOPEPTIDES

  

    

CELLCYCLE

    

  

CHREBP2

    

 

EIF

    

  

FCER1

 

     

GPCR

  

    

INTEGRIN

 

     

KERATINOCYTE

 

  

MAPK

   

 

NO1

    

  

P38MAPK

    

PPARA

   

 

 

TNFR1

     

0.000

 
  1. In each column, numbers denote the difference between the mean RMS of samples in a particular subtype and the mean RMS of remaining samples (e.g. RMS MLL - RMS Rest ). Numbers in red denote the pathway is tightly regulated in a subtype compared to the test, and opposite applies to the pathway in blue