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Table 2 Transcription factors related to the clustering

From: Peak shape clustering reveals biological insights

GATA-2 GATA binding protein 2
CEBPD CCAAT/Enhancer-Binding Protein Delta
HMGN3 High Mobility Group Nucleosome-binding domain-containing protein 3
TRIM28 TRIpartite Motif-containing 28
PML ProMyelocytic Leukemia protein
TAL-1 T-cell Acute Lymphocytic Leukemia protein 1
ZMIZ1 Zinc finger MIZ domain-containing protein 1
CCNT2 Cyclin-T2
  1. The eight transcription factors emerged as relevant for the peak shape clustering in Replicate 1, according to Gini index in all the random forest classifiers built (experiments on K562 cells). Combinatorial interaction analysis reveals that Cluster 2 is characterized by the simultaneous binding of all these eight proteins, together with GATA-1