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Table 2 Comparing AlignWise and other ORF finding software

From: AlignWise: a tool for identifying protein-coding sequence and correcting frame-shifts

 

Average

Number of ORFs found

Program

run time

Human EST

Rat cDNA

FaBox DNA

Random DNA

AlignFS

02:12:54

633

990

0

0

Genewise

01:56:41

633

990

0

0

AlignWise

02:21:29

633

990

0

0

AlignWise (fast)

00:27:12

627

987

0

0

AlignWise (fastest)

00:03:46

627

987

0

0

ESTscan

00:00:01

526

971

835

366

OrfPredictor

01:26:06

995

1000

999

999

TransDecoder

00:00:17

299

924

0

0

TransDecoder (pfam)

00:37:11

339

950

0

0

  1. AlignWise (fast) was set with the options ‘-a –T 2’, AlignWise (fastest) was run on a Mac 2 x 2.66 GHz 6-Core Intel Xeon using the option ‘-a –T 20’ to demonstrate the speed gains on a machine with more available CPUs. Only the longest ORF per starting transcript was counted in the TransDecoder and ESTscan outputs. The OrfPredictor run time includes running BLASTx