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Table 2 Pathways enriched by differentially expressed genes among TB, LTBI, and healthy control (HC)

From: Gene expression profiling identifies candidate biomarkers for active and latent tuberculosis

KEGG pathway ID Genes
TB vs. HC
 Cytokine-cytokine receptor interaction 04060 CCR6, IL7R, CCR7, FLT1, CCR2, TNFSF13B, FASLG, IL2RB, CD27, IL23A, TGFBR2
 Rheumatoid arthritis 05323 TLR4, IL23A, HLA-DOB, ATP6V0E2, FLT1, TNFSF13B
 Pathways in cancer 05200 MYC, ITGA6, FASLG, RASSF5, HSP90AA1, CASP8, TRAF4, TRAF5, TGFBR2, ETS1
 Graft-versus-host disease 05332 FASLG, KLRC1, PRF1, HLA-DOB
 MAPK signaling pathway 04010 FASLG, RRAS2, TGFBR2, MYC, RASA2, PRKACB, MAP3K1
LTBI vs. HC
 MAPK signaling pathway 04010 TNF, JUN, DUSP2, ATF4, NR4A1, FOS, DUSP5, DDIT3, PDGFRB, DUSP1
 Adipocytokine signaling pathway 04920 POMC, TNF, STK11, CAMKK2, NFKBIA, SOCS3
 Leishmaniasis 05140 TNF, JUN, FOS, NFKBIA
 Toll-like receptor signaling pathway 04620 TNF, JUN, FOS, NFKBIA
 Cytokine-cytokine receptor interaction 04060 TNF, CXCL2, TNFSF14, PDGFRB, OSM
LTBI vs. TB
 Chemokine signaling pathway 04062 GSK3B, CCR6, CXCL16, ARRB2, PIK3CG, NFKBIA, PRKACB
 Apoptosis 04210 CASP8, PIK3CG, NFKBIA, TNFRSF10B, PRKACB
 T cell receptor signaling pathway 04660 GSK3B, PTPRC, FOS, PIK3CG, NFKBIA
 Toll-like receptor signaling pathway 04620 LY96, CASP8, FOS, PIK3CG, NFKBIA
 B cell receptor signaling pathway 04662 GSK3B, FOS, PIK3CG, NFKBIA
  1. Benjamini-Hochberg adjusted p < 0.05