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Table 4 The Gene Ontology results of the subnetwork identified by RLRNPI-AEN for dataset GSE1456

From: Regularized logistic regression with network-based pairwise interaction for biomarker identification in breast cancer

Subnetwork

GO number

Ontology description

Adjusted p-value

TFG GPRASP1 TAC3 OFD1

GO:0043015

gamma-tubulin binding

3.07×10−2

 

GO:0043014

alpha-tubulin binding

3.07×10−2

SPTAN1 CRK FANCA

GO:0045309

protein phosphorylated amino acid binding

3.02×10−2

 

GO:0030507

spectrin binding

3.02×10−2

 

GO:0046875

ephrin receptor binding

3.02×10−2

 

GO:0042169

SH2 domain binding

3.02×10−2

 

GO:0051219

phosphoprotein binding

3.48×10−2

BACH2 ATF7 JUN

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

2.61×10−4

 

GO:0001012

RNA polymerase II regulatory region DNA binding

2.61×10−4

 

GO:0000976

transcription regulatory region sequence-specific DNA binding

2.61×10−4

 

GO:0000981

sequence-specific DNA binding RNA polymerase II transcription factor activity

2.61×10−4

 

GO:0000980

RNA polymerase II distal enhancer sequence-specific DNA binding

2.61×10−4

  1. The first column (Subnetwork) presents the elements of subnetwork of which the functional and biological relationship are analyzed based on the GO annotation