Fig. 2From: Leveraging protein quaternary structure to identify oncogenic driver mutationsIn this cartoon protein, the residues in domain A will be visited by the traveling salesman before any of the residues in Domain B or C. Thus the residues in domains B and C do not impact the remapping of domain A to \(\mathbb {R}\). Under iPAC however, every amino acid affects every other amino acid’s final position [25]Back to article page