Analysis tools for the interplay between genome layout and regulation

BMC Bioinformatics

Table 1 Top scoring periods for each of the seven major regulons of E. coli together with the respective p-values (first two columns)

TF name	Most significant period	p-value	Common^* period	p-value
CRP	186,317	0.0089	93,094	0.040
Lrp	5561	0.015	–	–
H-NS	750,416	0.0052	87,594	0.040
Fis	1,104,125	0.0006	–	–
IHF	1,117,262	0.00076	–	–
Fnr	323,570	0.0022	90,216	0.016
ArcA	180,888	0.00013	90,216	0.016

Common (more similar)* periods among all the significant periods from the same regulon and the respective p-values (3rd and 4th column). Four out of the seven major TFs share a similar significant period which is in par with previous reports of a 90-100kbp periods in E. coli. (*by “common” we refer to a period which is no more than 5 % different than its closest period in the group.)

ISSN: 1471-2105