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Table 4 The significant connections returned from sscMap using the breast cancer optimal gene signature based on the case study with dataset GSE15852, comparing 43 breast tumors with their paired normal tissues

From: A gene-signature progression approach to identifying candidate small-molecule cancer therapeutics with connectivity mapping

Compound Replicates cscore p value zscore SM PS
IC-86621 4 –0.079 5.0E-06 –4.84 1 1.00
Trichostatin A 182 –0.080 5.0E-06 –4.07 1 1.00
Semustine 4 –0.082 1.0E-04 –3.82 1 1.00
W-13 2 –0.091 8.0E-05 –3.77 1 1.00
Copper sulfate 4 –0.066 1.5E-04 –3.63 1 1.00
Exemestane 1 –0.136 2.8E-04 –3.58 1 1.00
Vorinostat 12 –0.087 1.9E-04 –3.47 1 1.00
Danazol 4 –0.053 2.5E-04 –3.43 1 1.00
Dexverapamil 1 –0.127 5.8E-04 –3.34 1 1.00
15-delta prostaglandin J2 15 –0.051 6.4E-04 –3.20 1 0.73