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Fig. 2 | BMC Bioinformatics

Fig. 2

From: tarSVM: Improving the accuracy of variant calls derived from microfluidic PCR-based targeted next generation sequencing using a support vector machine

Fig. 2

Sensitivity and specificity of filters using Sanger sequenced variants as gold standard for NS Cohort. Panel (a) shows the sensitivity of six different filters to detect 142 variants sequenced using Sanger. The default genotype filter has the highest sensitivity, which is not surprising because it was the principal norm for determining whether or not a variant should undergo Sanger sequencing from the CLC Genomics Workbench™. tarSVM is nearly as sensitive as the default genotype filter. Panel (b) displays the specificity of six filters. tarSVM is significantly more specific than the default genotype filter

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BMC Bioinformatics

ISSN: 1471-2105

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