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Fig. 1 | BMC Bioinformatics

Fig. 1

From: SCOUP: a probabilistic model based on the Ornstein–Uhlenbeck process to analyze single-cell expression data during differentiation

Fig. 1

The conceptual diagrams of the OU process (a) and SCOUP for multi-lineage differentiation (b). a The OU process represents a variable (i.e., expression of a gene g in a cell c) moving toward attractor (θ g ) with Brownian motion. The value at time t satisfies the normal distribution (see “Methods”). b Each lineage has distinct attractor (θ g1 and θ g2), and the lineage of a cell c is represented with latent value Z c . The expression of gene g in cell c is described with the mixture OU process

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BMC Bioinformatics

ISSN: 1471-2105

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