Accurate prediction of RNA-binding protein residues with two discriminative structural descriptors

BMC Bioinformatics

Table 7 The pairs of RNA-bounding and RNA-free proteins and performance differences between two types of proteins in different intervals of RMSD distribution (D_SN, D_SP, D_PPV, D_ACC, D_F_score and D_MCC stand for the prediction performance decrease in SN, SP, PPV, ACC, F_score and MCC for RNA-free proteins relative to that for RNA-bound ones)

RMSD distribution	Pairs	D_SN	D_SP	D_PPV	D_ACC	D_F_score	D_MCC
[0 Å, 1 Å)	7	0.039	0.023	0.046	0.024	0.051	0.058
[1 Å, 2 Å)	16	−0.040	0.060	0.099	0.048	0.079	0.069
[2 Å, 3 Å)	4	0.012	0.071	0.120	0.059	0.086	0.108
[3 Å, 4 Å)	3	0.125	0.029	0.067	0.036	0.090	0.112
[4 Å, 9 Å)	5	−0.008	0.037	0.072	0.027	0.048	0.051

ISSN: 1471-2105