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Table 2 Comparison with other approaches

From: Predicting existing targets for new drugs base on strategies for missing interactions

 

EN

IC

GPCR

NR

 

AUC|AUPR

AUC|AUPR

AUC|AUPR

AUC|AUPR

NetCBP

0.825|-

0.803|-

0.824|-

0.839|-

KronRLS

0.837|0.361

0.802|0.258

0.852|0.378

0.846|0.493

RLSm-comb-less

0.816|0.381

0.805|0.386

0.858|0.459

0.871|0.496

RLSm-comb

0.853|0.432

0.847|0.430

0.895|0.487

0.889|0.549

  1. RLSm-comb-less is our approach running with chemical-structure-based drug similarity and sequence-based target similarity. The bold entries denote the best results in terms of both AUC and AUPR
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BMC Bioinformatics

ISSN: 1471-2105

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