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Table 1 Examples of the variation of the transition probabilities at the sequence identity of 80 % between Markovian (P) and non-Markovian (\(\widetilde {P}\)) dynamics

From: Non-Markovian effects on protein sequence evolution due to site dependent substitution rates

Initial state

Final state

P(t)

\(\widetilde {P}(\tilde {t})\)

\(P(t)/\widetilde {P}(\tilde {t})\)

ATC

TGG

5.21·10−8

8.23·10−6

0.006

TTC

ATG

3.39·10−5

3.09·10−4

0.110

GTC

GTT

0.1507

0.0951

1.58

Ile

Val

0.104

0.076

1.4

Arg

Lys

0.064

0.049

1.3

Gly

Ile

0.0006

0.0022

0.3

  1. The first three rows involve substitutions in the framework of codons, while the last three are in the framework of amino acids