Table 2 Inference with Phenotypic Metadata
From: Reference-free deconvolution of DNA methylation data and mediation by cell composition effects
Data set | Permutaton P-values |
|---|---|
g[nt] | Tumor < 0.001 |
br-1[t] | Histology < 0.001; Age = 0.059; Size = 0.016 |
br-2[t] | Histology < 0.001; Age = 0.06 |
br-3[t] | ER < 0.001; Histology = 0.295; Age = 0.008; BSC = 0.297 |
bl-ov | Case < 0.001; Age = 0.999 |
bl-hn | Case < 0.001; Age < 0.001 |
BL-ra | Case < 0.001 |
BL-as | Log-arsenic < 0.001; Sex = 0.263 |
SP | Fraction = 0.994 |
BV+LV | Source = 0.013 |
UV-as | Log-arsenic = 0.515; Sex = 0.962 |
AR-as | Log-arsenic = 0.285; Sex = 0.505 |
AR[np] | Source < 0.001; Sex = 0.043; Age = 0.377 |
PL-as | Log-arsenic = 0.006; Sex = 0.451 |
L[np] | Source < 0.001 |
BR-tcga[n] | Age = 0.089; Race = 0.153 |
BR-tcga[t] | Age < 0.001; Race < 0.001; Staging = 0.013; ER < 0.001; HER2 < 0.001 |