Table 4 Counts of alleles in the unaffected sibs
Control | ||
|---|---|---|
A | a | |
B | \( \begin{array}{l}4\left({R}_{11}-{n}_{11}\right)+2\left({R}_{12}-{n}_{12}\right)\\ {}+2\left({R}_{21}-{n}_{21}\right)+\left({R}_{22}-{n}_{22}\right)\end{array} \) | \( \begin{array}{l}4\left({R}_{13}-{n}_{13}\right)+2\left({R}_{12}-{n}_{12}\right)\\ {}+2\left({R}_{23}-{n}_{23}\right)+\left({R}_{22}-{n}_{22}\right)\end{array} \) |
b | \( \begin{array}{l}4\left({R}_{31}-{n}_{31}\right)+2\left({R}_{32}-{n}_{32}\right)\\ {}+2\left({R}_{21}-{n}_{21}\right)+\left({R}_{22}-{n}_{22}\right)\end{array} \) | \( \begin{array}{l}4\left({R}_{33}-{n}_{33}\right)+2\left({R}_{32}-{n}_{32}\right)\\ {}+2\left({R}_{23}-{n}_{23}\right)+\left({R}_{22}-{n}_{22}\right)\end{array} \) |