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Table 5 Parameter settings for the power simulations

From: GCORE-sib: An efficient gene-gene interaction tool for genome-wide association studies based on discordant sib pairs

Scenario

Parameters (NF, DM, MAF, ES)a

Scen1

NF: 250,500,1000; DM: Additive; MAF: (0.2,0.2); ES: log(2)

Scen2

NF: 500; DM: Additive, Dominant, Recessive; MAF: (0.2,0.2); ES: log(2)

Scen3

NF: 500; DM: Additive; MAF: (0.2,0.2),(0.3,0.15); ES: log(2)

Scen4

NF: 500; DM: Additive; MAF: (0.2,0.2); ES: log(2), log(2.25)

  1. a NF number of families, DM disease model, MAF minor allele frequencies for the two SNPs, ES effect size for the interaction
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BMC Bioinformatics

ISSN: 1471-2105

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