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Fig. 10 | BMC Bioinformatics

Fig. 10

From: The tumor as an organ: comprehensive spatial and temporal modeling of the tumor and its microenvironment

Fig. 10

High vs. low oxygen secretion simulations. Top: graph of tumor cells showing that at a low oxygen level the tumor cells drop to almost zero at ~800ts but recover and reach 16,000 cells at ~1100ts, whereas at a high oxygen level they do not demonstrate a drop and reach 16,000 cells shortly after ~800ts. Bottom: images of these runs in SimuLife (left for low oxygen, right for high oxygen), presenting amounts on their left tab. Both images are presented at approximately the same time step – at low oxygen only few active tumor cells are present, at high oxygen the tumor consists of many cells where almost all are active

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