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Table 1 Comparison between different prediction servers

From: SHIVA - a web application for drug resistance and tropism testing in HIV

Server

PIs

NRTIs

NNRTIs

INIs

Mat. Inh.

Tropism

max. #

NGS

Run

Clinical

Detailed

       

sequences

data

timea

report

data

          

t

access

SHIVA

+

+

+

+

+

+

>100,000

allb

6.02 /

+

+

         

15.22

  

g2p [r e s i s t a n c e]

+

+

+

+

-

-

8

-

24.37

+

-

g2p [c o r e c e p t o r]

-

-

-

-

-

+

50c

454c

3.03

+

-

HIVdb

+

+

+

-

-

+

500

-

2.89

(+)

+

WebPSSM

-

-

-

-

-

+

500

-

7.91

-

+

  1. aaveraged over 10 runs with 8 protease and 50 V3 sequences, respectively
  2. bdata needs to be provided in FASTA format
  3. cUsing geno2pheno [454] it is possible to predict >100,000 sequences, however preprocessing of the data needs to be done offline
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BMC Bioinformatics

ISSN: 1471-2105

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