Fig. 3From: Optimized pipeline of MuTect and GATK tools to improve the detection of somatic single nucleotide polymorphisms in whole-exome sequencing dataNumber of False Negatives and True positives at different coverage levels. Three artificial tumors were created with 22, 25 and 25 SNVs, which had variant allelic fractions range of 0.02 to 0.25, 0.5 to 0.86, and 0.97 to 1.0, respectively. We counted the number of False Negatives (FN) and True positives (TP) for different levels of simulated sequencing coverageBack to article page