Table 2 RNA pathogenicity predictions in MToolBox with corresponding scores
rRNA prediction | rRNA Score | RNA pathogenicity score in MToolBox | tRNA Score | tRNA prediction |
|---|---|---|---|---|
Proven pathogenic | 5 | 1.000 | 20 | Definitely pathogenic |
0.950 | 19 | Definitely pathogenic | ||
0.900 | 18 | Definitely pathogenic | ||
0.850 | 17 | Definitely pathogenic | ||
Expectedly pathogenic | 4 | 0.800 | 16 | Definitely pathogenic |
0.750 | 15 | Definitely pathogenic | ||
0.700 | 14 | Definitely pathogenic | ||
0.650 | 13 | Possibly/definitely pathogenic | ||
Likely pathogenic | 3 | 0.600 | 12 | Possibly/definitely pathogenic |
0.550 | 11 | Possibly/definitely pathogenic | ||
0.500 | 10 | Possibly pathogenic | ||
0.450 | 9 | Possibly pathogenic | ||
Not enough evidence | 2 | 0.400 | 8 | Possibly pathogenic |
0.350 | 7 | Possibly pathogenic | ||
0.300 | 6 | Neutral | ||
0.250 | 5 | Neutral | ||
Undetermined | 1 | 0.200 | 4 | Neutral |
0.150 | 3 | Neutral | ||
0.100 | 2 | Neutral | ||
0.050 | 1 | Neutral | ||
Unlikely pathogenic | 0 | 0.000 | 0 | Neutral |