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Table 8 For each top 7 pairwise pathway in BC HER2: miRNA regulators of pathways, their expression levels in BC and in NS, and the statistical significance of the comparison (in terms of log Fold Change)

From: How interacting pathways are regulated by miRNAs in breast cancer subtypes

Pairwise pathways miRNA-r miRNA-r Exp. in BC miRNA-r Exp. in NS logFC
1. a) Acute Phase Response Signalling;
  b) HIF1 Signalling
Hsa-miR-429
Hsa-miR-3617
434.2326
0.209302
71.18391
0.045977
2.604998
1.078421
2. a) Atherosclerosis Signalling;
  b) Acute Phase Response Signalling
Hsa-miR-1910 1.581395 0.425287 1.501305
3. a) Axonal Guidance Signalling;
  b) CXCR4 Signalling
Hsa-miR-584
Hsa-miR-190
Hsa-miR-148b
Hsa-miR-449c
152.5116
11.60465
719.4651
5.651163
482.4253
31.05747
315.1839
0.068966
-1.30985
-1.02572
1.550205
5.430282
4. a) Axonal Guidance Signalling;
  b) P2Y Purigenic Receptor Signalling Pathway
Hsa-miR-92b
Hsa-miR-190
Hsa-miR-584
531.8605
11.60465
152.5116
171.1494
31.05747
482.4253
1.840728
-1.02572
-1.30985
5. a) HIF1 Signalling;
  b) Glioblastoma Multiforme Signalling
Hsa-miR-190b
Hsa-miR-1246
Hsa-miR-429
31.90698
0.255814
434.2326
6.137931
0.034483
71.18391
2.680854
1.277809
2.604998
6. a) HIF1 Signalling;
  b) Growth Hormone Signalling
Hsa-miR-490
Hsa-miR-429
5.395349
434.2326
0.298851
71.18391
4.276816
2.604998
7. a) Role of Macrophages. Fibroblasts and Endothelial Cells in Rheumatoid Arthritis;
  b) Growth Hormone Signalling
Hsa-miR-511-2
Hsa-miR-142
Hsa-miR-155
17.69767
11699.28
1931.163
56.51724
3246.46
616.9425
-1.49388
2.248187
1.707846