Table 8 For each top 7 pairwise pathway in BC HER2: miRNA regulators of pathways, their expression levels in BC and in NS, and the statistical significance of the comparison (in terms of log Fold Change)
From: How interacting pathways are regulated by miRNAs in breast cancer subtypes
Pairwise pathways | miRNA-r | miRNA-r Exp. in BC | miRNA-r Exp. in NS | logFC |
|---|---|---|---|---|
1. a) Acute Phase Response Signalling;   b) HIF1 Signalling | Hsa-miR-429 Hsa-miR-3617 | 434.2326 0.209302 | 71.18391 0.045977 | 2.604998 1.078421 |
2. a) Atherosclerosis Signalling;   b) Acute Phase Response Signalling | Hsa-miR-1910 | 1.581395 | 0.425287 | 1.501305 |
3. a) Axonal Guidance Signalling;   b) CXCR4 Signalling | Hsa-miR-584 Hsa-miR-190 Hsa-miR-148b Hsa-miR-449c | 152.5116 11.60465 719.4651 5.651163 | 482.4253 31.05747 315.1839 0.068966 | -1.30985 -1.02572 1.550205 5.430282 |
4. a) Axonal Guidance Signalling;   b) P2Y Purigenic Receptor Signalling Pathway | Hsa-miR-92b Hsa-miR-190 Hsa-miR-584 | 531.8605 11.60465 152.5116 | 171.1494 31.05747 482.4253 | 1.840728 -1.02572 -1.30985 |
5. a) HIF1 Signalling;   b) Glioblastoma Multiforme Signalling | Hsa-miR-190b Hsa-miR-1246 Hsa-miR-429 | 31.90698 0.255814 434.2326 | 6.137931 0.034483 71.18391 | 2.680854 1.277809 2.604998 |
6. a) HIF1 Signalling;   b) Growth Hormone Signalling | Hsa-miR-490 Hsa-miR-429 | 5.395349 434.2326 | 0.298851 71.18391 | 4.276816 2.604998 |
7. a) Role of Macrophages. Fibroblasts and Endothelial Cells in Rheumatoid Arthritis;   b) Growth Hormone Signalling | Hsa-miR-511-2 Hsa-miR-142 Hsa-miR-155 | 17.69767 11699.28 1931.163 | 56.51724 3246.46 616.9425 | -1.49388 2.248187 1.707846 |