Table 1 Secondary structure assessment of designed sequences. The predicted secondary structure accuracies of designed sequences by GAPSSIF, EvoDesign and Evolver on five proteins are estimated. PSS-Pred, PSI-Pred and Reprof are used as secondary structure prediction algorithms
From: Evaluating the accuracy of protein design using native secondary sub-structures
PDB ID_Chain | GAPSSIF | EvoDesign | Evolver | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reprof% | PSS% | PSI% | Reprof% | PSS% | PSI% | Reprof% | PSS% | |||||||||
B | Ave | B | Ave | B | Ave | B | Ave | B | Ave | B | Ave | B | Ave | B | Ave | |
1ZZK_A | 100 | 100 | 87.5 | 80.75 | 87.5 | 81.37 | 82 | 66.5 | 83 | 70.55 | 83 | 66.3 | 88.75 | 88.33 | 91.25 | 87.91 |
1XTE_A | 100 | 99.74 | 92.24 | 86.81 | 93.96 | 85.94 | 69 | 61.9 | 85 | 74.7 | 81 | 69.6 | 88.79 | 89.22 | 90.51 | 89.65 |
2VOU_A | 100 | 99.93 | 92.46 | 89.45 | 92.46 | 89.17 | 78 | 58.8 | 84 | 70.1 | 84 | 70.1 | 90.41 | 55.58 | 86.30 | 83.78 |
3I4O_A | 100 | 100 | 91.17 | 87.20 | 97.05 | 89.26 | 73 | 59.1 | 82 | 60.6 | 75 | 64 | 75 | 70.58 | 77.94 | 68.62 |
1R26_A | 100 | 100 | 96.15 | 91.24 | 92.30 | 87.49 | 84 | 68.2 | 95 | 77.6 | 95 | 76.5 | 91.34 | 91.02 | 93.26 | 92.30 |