Fusing literature and full network data improves disease similarity computation

BMC Bioinformatics

Table 1 Examples of false negatives and false positives with p-values from MedNetSim

Disease 1	Disease 2	P-value (MedSim)	P-value (NetSim)	P-value (MedNetSim)
False negatives
polycystic ovary syndrome	myocardial infarction	0.663	0.004	0.051
lipid storage disease	obesity	0.107	0.148	0.070
malaria	epilepsy syndrome	0.675	0.016	0.075
lipid storage disease	diabetes mellitus	0.108	0.156	0.075
False positives
impulse control disorder	narcissistic personality disorder	0.023	0.001	0.002
penile neoplasm	cecum cancer	0.023	0.007	0.004
pancreatic cancer	tubular adenocarcinoma	0.003	0.107	0.006
essential hypertension	hyperthyroidism	0.210	0.021	0.030

ISSN: 1471-2105