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Table 1 Division of 20 amino acid types, based on dipoles and volumes of side chains

From: Predicting protein-protein interactions via multivariate mutual information of protein sequences

No.

Group

Dipolescale

Volumescale

C 0

A,G,V

Dipole <1.0

Volume <50

C 1

C

1.0< Dipole <2.0 (form disulphide bonds)

Volume >50

C 2

D,E

Dipole >3.0 (opposite orientation)

Volume >50

C 3

F,I,L,P

Dipole <1.0

Volume >50

C 4

H,N,Q,W

2.0< dipole <3.0

Volume >50

C 5

K,R

Dipole >3.0

Volume >50

C 6

M,S,T,Y

1.0< dipole <2.0

Volume >50