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Table 1 Division of 20 amino acid types, based on dipoles and volumes of side chains

From: Predicting protein-protein interactions via multivariate mutual information of protein sequences

No. Group Dipolescale Volumescale
C 0 A,G,V Dipole <1.0 Volume <50
C 1 C 1.0< Dipole <2.0 (form disulphide bonds) Volume >50
C 2 D,E Dipole >3.0 (opposite orientation) Volume >50
C 3 F,I,L,P Dipole <1.0 Volume >50
C 4 H,N,Q,W 2.0< dipole <3.0 Volume >50
C 5 K,R Dipole >3.0 Volume >50
C 6 M,S,T,Y 1.0< dipole <2.0 Volume >50