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Table 1 FMAP performs pathway analysis of a Crohn’s disease study

From: FMAP: Functional Mapping and Analysis Pipeline for metagenomics and metatranscriptomics studies

Pathway

KO Count

Pathway Coverage

P-value

Flagellar assembly

23

0.622

2.977 × 10−25

Bacterial chemotaxis

13

0.500

4.331 × 10−13

Synthesis and degradation of ketone bodies

2

0.250

2.798 × 10−2

Pentose and glucuronate interconversions

8

0.131

9.820 × 10−4

Glutathione metabolism

5

0.125

1.077 × 10−2

Porphyrin and chlorophyll metabolism

10

0.094

3.110 × 10−3

Butanoate metabolism

7

0.085

2.087 × 10−2

Glycine, serine and threonine metabolism

7

0.075

3.810 × 10−2

Glyoxylate and dicarboxylate metabolism

7

0.074

4.201 × 10−2

Two-component system

23

0.054

1.933 × 10−2

  1. FMAP can automatically streamline its built-in pathway analysis. Here we show the FMAP pathway analysis results of a Crohn’s disease study (Sequence Read Archive number: SRP002423). KO Count: number of differentially abundant (DA) genes detected by FMAP; Pathway coverage: normalized coverage in each pathway; P-value: Fisher’s exact test used to assess the over/under representation of DA genes