Fig. 5
Stable modules are more readily annotated. Module gene over-representation in annotated gene sets (sum of –log10 p-value for the hypergeometric test) is visualized, for modules with varying stability, in the MSigDB and BTM collections. Stability is positively associated (Spearman’s ρ) with our ability to assign module to known biology (* p ≤ 0.05; † p ≤ 0.10) in many of these collections