Table 3 Silhouette Scores obtained using the transformed expression values from top 15% variance genes on applying different preprocessing techniques (using only PC2 and PC3, ignoring PC1)
From: GFS: fuzzy preprocessing for effective gene expression analysis
Raw | Scaled | Z-Score | Quantile | GFS | |
|---|---|---|---|---|---|
ALL (9 subtypes) | -0.243 | -0.186 | 0.017 | 0.027 | 0.217 |
ALL (2 subtypes) | 0.012 | 0.121 | 0.176 | 0.289 | 0.538 |
DMD | 0.049 | 0.047 | 0.426 | 0.486 | 0.530 |
Leukemia | 0.349 | 0.072 | 0.412 | 0.482 | 0.528 |