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Table 3 Silhouette Scores obtained using the transformed expression values from top 15% variance genes on applying different preprocessing techniques (using only PC2 and PC3, ignoring PC1)

From: GFS: fuzzy preprocessing for effective gene expression analysis

  Raw Scaled Z-Score Quantile GFS
ALL (9 subtypes) -0.243 -0.186 0.017 0.027 0.217
ALL (2 subtypes) 0.012 0.121 0.176 0.289 0.538
DMD 0.049 0.047 0.426 0.486 0.530
Leukemia 0.349 0.072 0.412 0.482 0.528
  1. Silhouette scores corresponding to GFS are the highest among all methods (highlighted in bold)