Prioritizing biological pathways by recognizing context in time-series gene expression data

BMC Bioinformatics

Table 2 Datasets used to evaluate contextTRAP

Dataset	Species	Keywords	Discovery rate	\|π\|	\|π ^∗\|
H5N1	Homo sapiens	Influenzas	0.30	295	15
Th17	Mus musculus	TGFB1 and IL6	0.21	291	29

H5N1 is a time-series gene expression data of homo sapiens and about highly pathogenic avian influenza H5N1 infection. Influenzas was used as keyword and Discovery rate was calculated as 0.30. Th17 is a time-series gene expression data of mus musculus and about T _H17 cell differentiation. TGFB1 and IL6 were used as keywords and Discovery rate was calculated as 0.21. |π| represents the number of total pathways and |π ^∗| is the number of the relevant pathways retrieved from DAVID with validated genes

ISSN: 1471-2105