Fig. 1

Protocol details. a Pipeline workflow. b Example of hierarchical clustering using toy data, portrayed as a tree where the leaves are DRPs and each inner node represents a cluster containing all DRPs in the sub-tree rooted at that node. Numbers at the branch point are the values of the distance metric when calculated across the two sub-trees that are being merged at the inner node. The red line is the empirically selected cutoff (here, 0.7); all sub-trees to the right of this cutoff represent the final clusters