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Table 1 Relevant studies on real-value RSA prediction

From: A hydrophobic spine stabilizes a surface-exposed α-helix according to analysis of the solvent-accessible surface area

Reference

Year

Regression method

Features

Ahmad [11]

2003

NN

Amino acid proportions

Yuan [12]

2004

SVR

Amino acid proportions

Adamczak [13]

2004

NN

PSSM

Wang [14]

2005

MLR

Amino acid proportions, PSSM, and sequence length

Garg [15]

2005

NN

PSSM and secondary structure

Nguyen [16]

2006

Two-stage SVR

PSSM

Chang [17]

2008

Two-stage SVR

enhance PSSM and sequence length

Iqbal [18]

2015

Basic exact regression

PSSM, PCPs and disorder probability

Fan [19]

2015

GBRT

PSSM, secondary structure, and native disorder

Zhang [20]

2015

SVR

PSSM, PCPs, secondary structure, disorder probability

SVR-RSA

2016

SVR

PSSM, PCPs, and sequence length