The role of nucleotide composition in premature termination codon recognition

BMC Bioinformatics

Table 2 Comparison of MFE absolute values between transcripts with small, moderate, and large stability change, both upstream to the TC and along the 3’UTR

Compared transcripts		Dunn test			Effect size
Compared transcripts		Q value	Critical Q	Decision	Effect size
Large vs. small stability change	Upstream to the TC	0.55	2.38	Fail to reject H ₀	0.03
Large vs. small stability change	Along the 3’UTR	3.29	2.38	Reject H ₀	0.15
Large vs. moderate stability change	Upstream to the TC	N/A	2.38	N/A	0.02
Large vs. moderate stability change	Along the 3’UTR	2.03	2.38	Fail to reject H ₀	0.10
Moderate vs. small stability change	Upstream to the TC	0.17	2.38	Fail to reject H ₀	0.01
Moderate vs. small stability change	Along the 3’UTR	1.23	2.38	Fail to reject H ₀	0.06

H ₀ represents the null hypothesis of no difference between the two transcript groups. Effect size is defined as |A − 0.5|, where A is the common language effect size

ISSN: 1471-2105