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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Robust differential expression analysis by learning discriminant boundary in multi-dimensional space of statistical attributes

Fig. 1

The up- and down-regulation tails may show different characteristics in the joint distribution of two basic attributes. Two typical examples are shown here. a A RNA-seq dataset GSE49114 (control vs. Schisto-PH): Y-axis – the moderated t-statistic from voom; X-axis – the Wald statistic of the NB-based differential expression test from DESeq2. b A DNA methylation dataset GSE34099 (Rett syndrome vs. control): Y-axis – the moderated t-statistic from limma; X-axis – the moderated t-statistic from voom. GSE49114 and GSE34099 were downloaded from the Gene Expression Omnibus database (http://www.ncbi.nlm.nih.gov/geo/)

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BMC Bioinformatics

ISSN: 1471-2105

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