Table 2 Demographic and clinical data of subjects in the biomarker discovery cohort

N

20

19

46

47

72

72

3

3

Age

56 ± 7

54 ± 6

63 ± 8

63 ± 9

65 ± 11

65 ± 11

43 ± 4

44 ± 3

Female (%)

52.6

40.0

23.6

23.4

38.9

37.5

33.3

33.3

Gensini plaque score

0 ± 0

42 ± 28

0 ± 0

80 ± 31

n.a.

n.a.

n.a.

n.a.

Diabetes (%)

5.0

21.1

0

23.4

8.3

27.8

100

100

Current smoker (%)

20.0

21.1

4.3

6.4

4.2

22.2

33.3

33.3

Systolic blood pressure (mm Hg)

137 ± 18

133 ± 15

140 ± 17

139 ± 25

136 ± 19

147 ± 21

111 ± 10

122 ± 14

Diastolic blood pressure (mm Hg)

81 ± 10

78 ± 10

82 ± 11

79 ± 13

70 ± 11

76 ± 11

80 ± 10

87 ± 10

Total cholesterol (mmol/l)

5.2 ± 1.2

5.9 ± 0.3

5.6 ± 1.1

4.1 ± 0.9

6.2 ± 1.1

6.0 ± 1.2

4.8 ± 0.4

5.4 ± 0.7

HDL cholesterol (mmol/l)

1.2 ± 0.3

1.2 ± 0.3

1.5 ± 0.4

1.2 ± 0.3

1.5 ± 0.4

1.2 ± 0.4

1.3 ± 0.5

1.3 ± 0.6

Trigycerides (mmol/l)

2.0 ± 1.0

1.8 ± 0.8

1.6 ± 0.9

2.2 ± 1.0

n.a.

n.a.

1.1 ± 0.8

1.1 ± 0.5