Skip to main content

Table 5 Average per-target correlation and loss on Stage 1 and Stage 2 for DeepQA and its training features on CASP11. The significance between DeepQA and individual feature was assessed by Wilcoxon signed ranked sum paired t-test*, and its P-value was included to represent the improvement of DeepQA against its input features

From: DeepQA: improving the estimation of single protein model quality with deep belief networks

QA methods

Corr. onstage 1/P-value

Loss on stage 1/P-value

Corr. on stage 2/P-value

Loss on stage 2/P-value

DeepQA

0.64/-

0.09/-

0.42/-

0.06/-

Dope

0.54/1.77E-06

0.11/0.0421

0.30/4.63E-10

0.08/2.76E-01

EC score

0.37/4.29E-11

0.18/5.71E-07

0.02/3.23E-14

0.14/2.08E-10

GOAP score

0.54/2.74E-05

0.13/0.0016

0.31/5.07E-07

0.07/1.06E-01

ModelEvaluator score

0.56/0.0001

0.10/0.2160

0.28/1.87E-09

0.08/1.99E-02

OPUS score

0.43/2.14E-11

0.12/0.0588

0.30/4.53E-09

0.08/3.54E-01

Qprob score

0.63/0.8080

0.09/0.9382

0.38/8.63E-03

0.06/7.12E-01

RWplus score

0.54/4.80E-06

0.14/0.0009

0.30/9.41E-09

0.08/4.49E-02

SP score

0.47/3.07E-10

0.14/0.0067

0.26/6.17E-10

0.10/1.10E-05

SU score

0.50/3.78E-09

0.18/4.94E-07

0.19/6.34E-11

0.11/3.95E-07

Mean

0.52/0.09

0.13/0.14

0.27/0.00

0.09/0.17

  1. * The Wilcoxon signed ranked sum paired t-test was performed on the correlation and loss of targets between each feature against DeepQA